Chimeric Virus-Like Particles (VLPs) Designed from Shrimp Nodavirus (MrNV) Capsid Protein Specifically Target EGFR-Positive Human Colorectal Cancer Cells

Researchers created three different types of chimeric MrNV VLPs that had specificity toward the epidermal growth factor receptor (EGFR), a cancer cell biomarker, by incorporating the EGFR-specific GE11 peptide at three different locations within the host cell recognition site of the capsid.