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Proteomics-Derived Basal Biomarker DNA-PKcs Is Associated with Intrinsic Subtype and Long-Term Clinical Outcomes in Breast Cancer

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The authors evaluated DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in clinically-annotated breast cancer tissue microarrays and correlated results with immune biomarkers. They found that high expression of DNA-PKcs was significantly associated with stromal and CD8+ tumor infiltrating lymphocytes.
[npj Breast Cancer]
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