Scientists presented a transgenic, TAR DNA-binding protein-43 (TDP-43)-A315T, mouse model expressing an Amyotrophic Lateral Sclerosis (ALS) phenotype and demonstrated the presence of ubiquitinated cytoplasmic TDP-43 aggregates with > 80% cell death by 28 days post differentiation in vitro.
[Scientific Reports]
7992332
{7992332:AAAAAAAA}
apa
50
1
166692
https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/