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Genetic Variations of DNA Bindings of FOXA1 and Co-Factors in Breast Cancer Susceptibility

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Researchers developed a statistical framework to analyze extensive ChIP-seq and GWAS data, identified 22 breast cancer risk-associated transcription factors (TFs), and showed that FOXA1 and co-factors formed a core TF-transcriptional network regulating the susceptibility genes.
[Nature Communications]
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