Researchers reported that the conjunct activity of two orphan nuclear receptors, Esrrb and Nr5a2, paralleled the importance of that of Oct4 and Sox2 in naïve mouse ESCs. By occupying a large common set of regulatory elements, these two factors controlled the binding of Oct4, Sox2 and Nanog to DNA.
[Development]
7992332
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apa
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1
166756
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