Chronic Mineral Oil Administration Increases Hepatic Inflammation in Wild Type Mice Compared to Lipocalin 2 Null Mice

Scientists investigated the roles of Lipocalin 2 (LCN2) in chronic inflammation and fibrosis, using repeated carbon tetrachloride in mineral-oil injection. Hepatic and serum LCN2 levels were remarkably higher in the mineral oil-injected wild type group compared to the CCl4.