Scientists demonstrated that the autoimmunity caused by the the Drosophila tuSz1 mutant strain was the result of two mutations: a mutation in the GCS1 gene that disrupted N-glycosylation of ECM proteins covering the fat body, and a mutation in the Drosophila Janus Kinase ortholog that caused precocious activation of hemocytes.
[Proceedings of the National Academy of Sciences of the United States of America]
7992332
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apa
50
1
166981
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