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Proinflammatory Cytokines Promote TET2-Mediated DNA Demethylation during CD8 T Cell Effector Differentiation

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To gain insight into the signaling determinants of effector-associated DNA methylation programming among CD8 T cells, scientists explored the role of interleukin-12 in the imprinting of IFNg expression during CD8 T cell priming.
[Cell Reports]
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