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Impaired Neural Differentiation of MPS IIIA Patient Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells

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Investigators demonstrated the generation of Mucopolysaccharidosis type IIIA (MPS IIIA) iPSCs, and neural progenitor cells, the latter of which display reduced proliferation and neurogenic capacity.
[Molecular Genetics and Metabolism Reports]
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