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Repositioning of a Novel GABA-B Receptor Agonist, AZD3355 (Lesogaberan), for the Treatment of Non-Alcoholic Steatohepatitis

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Lesogaberan’s potential efficacy in non-alcoholic steatohepatitis (NASH) was tested in human stellate cells, human precision cut liver slices, and in vivo in a well-validated murine model of NASH.
[Scientific Reports]
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