K15 Promoter-Driven Enforced Expression of NKIRAS Exhibits Tumor Suppressive Activity against the Development of DMBA/TPA-Induced Skin Tumors

Researchers clarified how NKIRAS acted on cellular transformation, and generated transgenic mice in which NKIRAS2 was forcibly expressed using a cytokeratin 15 promoter, which was mainly activated in follicle bulge cells.