Home Newsletters Extracellular Matrix News RCAN1.4 Attenuates Renal Fibrosis through Inhibiting Calcineurin-Mediated Nuclear Translocation of NFAT2

RCAN1.4 Attenuates Renal Fibrosis through Inhibiting Calcineurin-Mediated Nuclear Translocation of NFAT2

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The authors indicated that RCAN1.4 expression was impaired both in unilateral ureteral obstruction-induced renal fibrosis in vivo and TGF-β1-induced renal fibrosis in vitro. However, knocking in of RCAN1.4 suppressed the production of ECM both in vivo and in vitro.
[Cell Death Discovery]
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