Home Newsletters Human Immunology News The Unfolded Protein Response Links Tumor Aneuploidy to Local Immune Dysregulation

The Unfolded Protein Response Links Tumor Aneuploidy to Local Immune Dysregulation

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Using a single somatic copy number alteration score inclusive of whole-chromosome, chromosome arm, and focal alterations in a pan-cancer analysis of 9,375 samples in The Cancer Genome Atlas database, scientists found an inverse correlation with a cytotoxicity score across disease stages.
[EMBO Reports]

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