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Single-Cell Analysis Reveals EP4 as a Target for Restoring T Cell Infiltration and Sensitizing Prostate Cancer to Immunotherapy

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Investigators identified EP4 as a specific target for prostate cancer immunotherapy and demonstrated that YY001 inhibited the growth of prostate tumors by regulating the immune microenvironment and strongly synergized with anti-programmed cell death protein-1 antibodies.
[Clinical Cancer Research]

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Abstract
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