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ASC Speck Formation after Inflammasome Activation in Primary Human Keratinocytes

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Scientists showed that UVB provoked apoptosis-associated speck-like protein (ASC) speck formation in human primary keratinocytes prior to cell death, and that specks were, opposed to the perinuclear cytosolic localization in myeloid cells, formed in the nucleus.
[Oxidative Medicine and Cellular Longevity]
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