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TGF-Beta Pathway Inhibition as the Therapeutic Acceleration of Diabetic Bone Regeneration

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Scientists investigated the gene expression profile of bones from type 2 diabetic mice and wild-type mice by comparative microarray analysis before and after placing tibial defects and examined the expression of several osteogenesis- and osteoclastogenesis-related markers by quantitative real-time polymerase chain reaction.
[Journal of Orthopaedic Research]
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Abstract
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