The receptor tyrosine kinase AXL has been identified as an entry receptor for Zika virus (ZIKV) in a cell type-specific manner. Interestingly, AXL was frequently overexpressed in glioblastoma (GBM) patients. The authors demonstrated that ZIKV entry into GBM cells in vitro was mediated by the AXL receptor.
[Molecular Therapy-Oncolytics]
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