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Overcoming Prostate Cancer Drug Resistance with a Novel Organosilicon Small Molecule

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A major challenge to the treatment of advanced prostate cancer (PCa) is the development of resistance to androgen-deprivation therapy (ADT) and chemotherapy. GH1504 exhibited potent in vitro cytotoxicity in a broad spectrum of human cancer cells, including PCa cells refractory to ADT and chemotherapy.
[Neoplasia]

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