Materials-Driven Fibronectin Assembly on Nanoscale Topography Enhances Mesenchymal Stem Cell Adhesion, Protecting Cells from Bacterial Virulence Factors and Preventing Biofilm Formation

The authors used a poly ethyl acrylate polymer coating on titanium nanowires to spontaneously organize fibronectin and to deliver bone morphogenetic protein 2 to enhance MSC adhesion and osteospecific signaling.