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Lysophosphatidic Acid Shifts Metabolic and Transcriptional Landscapes to Induce a Distinct Cellular State in Human Pluripotent Stem Cells

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Scientists reported that the metabolic landscape of human PSCs was shifted by signaling lipid lysophosphatidic acid (LPA), which naturally exists. LPA led to a distinctive transcriptome profile that was not associated with de novo lipogenesis.
[Cell Reports]
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