Home Newsletters Endothelial Cell News Regulation of Blood–Brain Barrier Integrity by Microbiome-Associated Methylamines and Cognition by Trimethylamine...

Regulation of Blood–Brain Barrier Integrity by Microbiome-Associated Methylamines and Cognition by Trimethylamine N-oxide

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Scientists used an integrated in vitro/in vivo approach to show that physiologically relevant concentrations of the dietary methylamine trimethylamine N-oxide enhanced blood-brain barrier integrity and protected it from inflammatory insult, acting through the tight junction regulator annexin A1.
[Microbiome]

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