Scientists generated models of sarcomas bearing kinase fusions and assessed their response to molecularly targeted therapy. Immortalized, untransformed human MSCs, a putative cell-of-origin of sarcomas, were modified using CRISPR-Cas9 to harbor a RET chromosomal translocation.
[Cancer Research]
7992332
{7992332:BBBBBBBB}
apa
50
1
171085
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