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Multi-Omic Analysis Reveals Divergent Molecular Events in Scarring and Regenerative Wound Healing

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Scientists profiled scarring versus YAP-inhibition-induced wound regeneration at the transcriptional, protein, and tissue levels, and showed that disrupting YAP mechanotransduction yielded regenerative repair by fibroblasts with activated Trps1 and Wnt signaling.
[Cell Stem Cell]
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AbstractGraphical Abstract
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