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Attenuation of SARS-CoV-2 Infection by Losartan in Human Kidney Organoids

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Using iPSC derived-kidney organoids, SARS-CoV-1, SARS-CoV-2 and MERS-CoV tropism, defined by the paired expression of a host receptor and protease, was identified primarily amongst proximal tubule cells.
[iScience]
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