Histone Deacetylase Inhibitors Attenuated Interleukin-1β-Induced Chondrogenesis Inhibition in Synovium-Derived Mesenchymal Stem Cells of the Temporomandibular Joint

Synovium-derived MSCs (SMSCs) were isolated from synovium specimens of patients undergoing temporomandibular joint surgery. Chondrogenic differentiation potential of SMSCs was evaluated in vitro in the control, IL-1β stimulation, and IL-1β stimulation with histone deacetylase inhibitors groups.