Investigators found that pregnancies in mice with EZH2-deficient decidual stromal cells frequently failed by mid-gestation, with the decidua showing ectopic myofibroblast formation, peri-embryonic collagen deposition, and gene expression profiles associated with transforming growth factor β (TGF-β)-driven fibroblast activation and fibrogenic ECM remodeling.
[Cell Reports]
7992332
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apa
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