Home Newsletters Prostate Cell News ERK1/2 Inhibits Cullin 3/SPOP-Mediated PrLZ Ubiquitination and Degradation to Modulate Prostate Cancer...

ERK1/2 Inhibits Cullin 3/SPOP-Mediated PrLZ Ubiquitination and Degradation to Modulate Prostate Cancer Progression

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Researchers reported that prostate leucine zipper (PrLZ) could be degraded by SPOP. PrLZ abundance was elevated in SPOP-mutant expressing prostate cancer cell lines and patient specimens.
[Cell Death & Differentiation]

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