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OSI-027 Inhibits the Tumorigenesis of Colon Cancer Through Mediation of C-myc/FOXO3a/PUMA Axis

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OSI-027 dose-dependently reduced colon cancer cell viability through inducing the cell apoptosis and induced the apoptosis of colon cancer cells via upregulation of p53-upregulated modulator of apoptosis (PUMA).
[Cell Biology International]
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Abstract
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