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Matrix Stiffness-Induced Upregulation of Histone Acetyltransferase KAT6A Promotes Hepatocellular Carcinoma Progression through Regulating SOX2 Expression

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Scientists demonstrated that lysine acetyltransferase 6 A (KAT6A) expression was upregulated in HCC tissues and cell lines. Clinical analysis showed that increased KAT6A was significantly associated with malignant prognostic features and shorter survival.
[British Journal of Cancer]
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Abstract
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