Home Newsletters Cell Therapy News CCR7 Expression in CD19 Chimeric Antigen Receptor-Engineered Natural Killer Cells Improves Migration...

CCR7 Expression in CD19 Chimeric Antigen Receptor-Engineered Natural Killer Cells Improves Migration toward CCL19-Expressing Lymphoma Cells and Increases Tumor Control in Mice with Human Lymphoma

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Since Natural Killer (NK)-92 cells do not spontaneously express CCR7, clinical-grade activated NK cells were transfected with a non-viral vector containing the CCR7 receptor, an anti-CD19 CAR and a high-affinity CD16 Fc receptor.
[Cytotherapy]
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Abstract
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