NewslettersHematopoiesis News Inability to Phosphorylate Y88 of p27Kip1 Enforces Reduced p27 Protein Levels and Accelerates Leukemia Progression By Britya Ghosh - May 24, 2022 0 To investigate the physiological significance of p27 tyrosine phosphorylation, scientists generated a knock-in mouse model where Y88 was replaced by phenylalanine. [Leukemia] Full Article