NewslettersCancer Stem Cell News Platinum-Induced Mitochondrial OXPHOS Contributes to Cancer Stem Cell Enrichment in Ovarian Cancer By lbeveridge - June 2, 2022 0 The effect of cisplatin on mitochondrial activity was assessed by JC1 staining and expression of OXPHOS genes by RT-qPCR. Cisplatin-induced changes in Sirtuin 1 levels and activity were assessed by western blot. [Journal of Translational Medicine] Full Article