NewslettersExtracellular Matrix NewsHepatic Cell News Syndecan-1 in Liver Pathophysiology By Danielle Corrigan - June 17, 2022 0 290 Syndecan-1 represents the major proteoglycan of the liver, expressed by hepatocytes and cholangiocytes, and its elevated expression is a characteristic feature of liver diseases. [American Journal of Physiology-Cell Physiology] Abstract