NewslettersNeural Cell NewsOrganoid News Hypoxia-Induced HMGB1 Promotes Glioma Stem Cells Self-Renewal and Tumorigenicity via RAGE By lbeveridge - August 8, 2022 0 Investigators reported that high mobility group box 1 (HMGB1) was overexpressed in human glioblastoma specimens. Hypoxia promoted the expression and secretion of HMGB1 in glioma stem cells [iScience] Abstract