Sirtuin 6 Inhibition Protects against Glucocorticoid-Induced Skeletal Muscle Atrophy by Regulating IGF/PI3K/AKT Signaling

Researchers studied SIRT6, a chromatin-associated deacetylase, and its indirect influence in the regulation of glucocorticoid-induced muscle wasting by modulating IGF/PI3K/AKT signaling.