NewslettersHuman Immunology News How We Diagnose and Treat Acute Graft-versus-Host Disease after Solid Organ Transplantation By lbeveridge - November 22, 2022 0 Signs and symptoms are nonspecific and include a rash, nausea, appetite loss, diarrhea, and cytopenias. Pancytopenia from marrow-directed GVHD is the primary driver of mortality. [Blood] Abstract