NewslettersImmune Regulation News The Lysosomal Ragulator Complex Activates NLRP3 Inflammasome In Vivo via HDAC6 By Laurisa Dohm - December 2, 2022 0 Deficiency of Lamtor1, an essential component of the Ragulator complex, abrogated NLRP3 inflammasome activation in murine macrophages and human monocytic cells. [EMBO Journal] AbstractGraphical Abstract