Investigators reported the discovery of a series of new AXL PROTAC degraders. One representative compound 6n potently depleted AXL with a DC50 value of 5 nM in MDA-MB-231 TNBC cells.
[European Journal Of Medicinal Chemistry]
Home Newsletters Discovery of AXL Degraders with Improved Potencies in Triple-Negative Breast Cancer (TNBC)...
