NewslettersHematopoiesis NewsHuman Immunology News Intrathymic Dendritic Cell-Biased Precursors Promote Human T Cell Lineage Specification through IRF8-Driven Transmembrane TNF By Laurisa Dohm - January 31, 2023 0 In vitro recapitulation of TNF receptor 2 (TNFR2) signaling, by providing low-density membrane-bound precursor form of the cytokine TNF or a selective TNFR2 agonist, enhanced the generation of human T cell precursors. [Nature Immunology] Full Article