NewslettersIntestinal Cell NewsOrganoid News The SMARCA4R1157WM Mutation Facilitates Chromatin Remodeling and Confers PRMT1/SMARCA4 Inhibitors Sensitivity in Colorectal Cancer By Laurisa Dohm - March 16, 2023 0 Researchers showed that the SMARCA4R1157WM mutant reinforced the transcriptional expression of EGFR and TNS4 to promote the proliferation of colorectal cancer cells and patient-derived tumor organoids. [NPJ Precision Oncology] Full Article