NewslettersNeural Cell News Mechanism of STMN2 Cryptic Splice-Polyadenylation and Its Correction for TDP-43 Proteinopathies By Jamie Kang - March 21, 2023 0 Scientists determined that TDP-43 binding in the first intron of the STMN2 pre-mRNA sterically blocked access of RNA processing factors that would otherwise recognize and use a cryptic 3′ splice site. [Science] Abstract