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Blocking Dectin-1 Prevents Colorectal Tumorigenesis by Suppressing Prostaglandin E2 Production in Myeloid-Derived Suppressor Cells and Enhancing IL-22 Binding Protein Expression

By
Noshin Noorjahan
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0
Investigators found that azoxymethane-dextran-sodium-sulfate-induced and ApcMin-induced intestinal tumorigenesis were suppressed in Clec7a−/− mice independently from commensal microbiota.
[Nature Communications]
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