NewslettersPulmonary Cell News KRASG12C Mutation-Induced TOPK Overexpression Contributes to Tumour Progression in Non-Small Cell Lung Cancer By Jamie Kang - May 25, 2023 0 The overexpression of TOPK significantly promoted the malignant phenotype of A549 cells, and TOPK silencing impaired the malignant phenotype with KRASG12C mutation. [Journal Of Cellular And Molecular Medicine] Full Article