Ethanol Causes Cell Death and Neuronal Differentiation Defect During Initial Neurogenesis of the Neural Retina by Disrupting Calcium Signaling in Human Retinal Organoids

Researchers utilized the hESC derived retinal organoids (hROs) to recapitulate the initial retinal neurogenesis and found that 1% (v/v) ethanol slowed the growth of hROs by inducing robust cell death and retinal ganglion cell differentiation defect.