NewslettersImmune Regulation News Mutations from Patients with IPEX Ported to Mice Reveal Different Patterns of FoxP3 and Treg Dysfunction By Laurisa Dohm - August 25, 2023 0 To understand the functional impact of mutations across FoxP3 domains, without genetic and environmental confounders, six human FOXP3 missense mutations were engineered into mice. [Cell Reports] Full ArticleGraphical Abstract