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Cigarette Smoke Restricts the Ability of Mesenchymal Cells to Support Lung Epithelial Organoid Formation

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The authors assessed the effect of cigarette smoke-exposure and the endoplasmic reticulum stress inducer Thapsigargin on Wnt/β-catenin signaling activation in MRC-5 fibroblasts, and on their ability to support lung epithelial organoid formation.
[Frontiers in Cell and Developmental Biology]
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