NewslettersOrganoid News NOTCH3 Signaling Controls Human Trophoblast Stem Cell Expansion and Differentiation By Noshin Noorjahan - November 23, 2023 0 Using trophoblast stem cells, trophoblast organoids, and primary cytotrophoblasts of early pregnancy, scientists showed that autocrine NOTCH3 signaling controlled human placental expansion and differentiation. [Development] Abstract