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Delivery of a BET Protein Degrader via a CEACAM6-Targeted Antibody–Drug Conjugate Inhibits Tumor Growth in Pancreatic Cancer Models

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To improve PDAC therapy, researchers established screening systems based on organoid and co-culture technologies and found a payload of antibody–drug conjugate, a bromodomain and extra-terminal (BET) protein degrader named EBET.
[Nature Communications]
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