NewslettersESC & iPSC News PRODH Safeguards Human Naive Pluripotency by Limiting Mitochondrial Oxidative Phosphorylation and Reactive Oxygen Species Production By Noshin Noorjahan - March 14, 2024 0 Investigators reported that, proline dehydrogenase (PRODH), a mitochondria-localized proline metabolism enzyme, was dramatically upregulated in naive hESCs compared to their primed counterparts. [EMBO Reports] Full ArticleGraphical Abstract