Investigators uncovered CNOT3, a subunit of the CCR4-NOT complex, as an essential modulator of translation in myeloid leukemia. Elevated CNOT3 expression correlated with unfavorable outcomes in patients with AML.
[Nature Communications]
Home Newsletters Hematopoiesis News Translation Efficiency Driven by CNOT3 Subunit of the CCR4-NOT Complex Promotes Leukemogenesis
